{"id":4969,"date":"2022-04-01T16:05:02","date_gmt":"2022-04-01T14:05:02","guid":{"rendered":"https:\/\/www.ichthyol.de\/raw-materials-for-corporate-customers\/ichthyol-pale\/"},"modified":"2023-04-24T09:38:02","modified_gmt":"2023-04-24T07:38:02","slug":"ichthyol-pale","status":"publish","type":"page","link":"https:\/\/www.ichthyol.de\/en\/raw-materials-for-corporate-customers\/ichthyol-pale\/","title":{"rendered":"Ichthyol<sup>\u00ae<\/sup> Pale"},"content":{"rendered":"<section class=\"l-section wpb_row us_custom_5fb9c346 en_opener en_opener_lp height_auto width_full with_slider\" id=\"introduction\"><div class=\"l-section-slider\"><div class=\"w-slider style_none fit_cover nav_none count_1\"><div class=\"w-slider-h\" aria-hidden=\"true\"><div class=\"royalSlider\"><div class=\"rsContent\"><a class=\"rsImg\" data-rsw=\"1920\" data-rsh=\"1440\" href=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2023\/03\/icon_IP_einfuehrungWebseite1920.jpg\"><span data-alt=\"\"><\/span><\/a><\/div><\/div><img decoding=\"async\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2023\/03\/icon_IP_einfuehrungWebseite1920.jpg\" width=\"1920\" height=\"1440\" loading=\"lazy\" alt=\"\" title=\"\"><\/div><div class=\"w-slider-json\" onclick='return {&quot;autoScaleSlider&quot;:true,&quot;addActiveClass&quot;:true,&quot;loop&quot;:true,&quot;fadeInLoadedSlide&quot;:false,&quot;slidesSpacing&quot;:0,&quot;imageScalePadding&quot;:0,&quot;numImagesToPreload&quot;:2,&quot;arrowsNav&quot;:false,&quot;arrowsNavAutoHide&quot;:false,&quot;transitionType&quot;:&quot;move&quot;,&quot;transitionSpeed&quot;:0,&quot;block&quot;:{&quot;moveEffect&quot;:&quot;none&quot;,&quot;speed&quot;:300},&quot;thumbs&quot;:{&quot;fitInViewport&quot;:false,&quot;firstMargin&quot;:false,&quot;spacing&quot;:4},&quot;controlNavigation&quot;:&quot;none&quot;,&quot;autoScaleSliderWidth&quot;:1920,&quot;autoScaleSliderHeight&quot;:1440}'><\/div><\/div><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default\"><div class=\"vc_col-sm-12 vc_col-lg-8 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container en_opener_img\"><div class=\"vc_column-inner us_custom_9a841f71\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><div class=\"vc_col-sm-12 vc_col-lg-4 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container en_opener_text\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row us_custom_ea92c9f7 via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Ichthyol\u00ae Pale&#8221; font_container=&#8221;tag:h1|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p style=\"text-align: center;\">By the name of <strong>Ichthyol\u00ae Pale<\/strong>, Ichthyol-Gesellschaft offers <strong>pale sulfonated shale oil<\/strong> for use in <strong>cosmetic skin and hair care<\/strong>. Convince yourself of the quality and proven efficacy profile of this <strong>well-tolerated<\/strong> substance on the following pages.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-btn-wrapper align_center\"><a class=\"w-btn us-btn-style_1\" target=\"_blank\" rel=\"nofollow\" href=\"\/wp-content\/uploads\/2023\/03\/IchthyolPale_Flyer2022.pdf\"><span class=\"w-btn-label\">Flyer<\/span><\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_c70c97eb en_overflow_hide height_large\" id=\"quality\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default reversed stacking_default\"><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;A guarantee for good quality&#8221; use_theme_fonts=&#8221;yes&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Flaking scalp and skin problems<\/strong> as well as <strong>skin impurities<\/strong> are often triggered by interaction of different factors. <strong>Ichthyol\u00ae Pale<\/strong> provides the basis for a <strong>functionally combined approach<\/strong> to solving skin problems.<\/p>\n<p>In cosmetics, <strong>Ichthyol\u00ae Pale<\/strong> is one of the <strong>well-documented substances of natural origin<\/strong>. The <strong>pale sulfonated shale oil<\/strong> is manufactured by Ichthyol-Gesellschaft according to the principles of <strong>good manufacturing practice (GMP)<\/strong> in consistently good quality.<\/p>\n<p><strong>Ichthyol\u00ae Pale<\/strong> is characterized by <strong>high purity, good tolerability<\/strong>, galenic preferences and versatility in the care of problem skin.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>The main features at a glance<\/h3>\n<ul>\n<li>natural origin (from an organic matter-rich limestone)<\/li>\n<li>high purity<\/li>\n<li>high safety factor<\/li>\n<li>good tolerability<\/li>\n<li>broad spectrum of action (scientifically proven)\n<ul>\n<li>reduces dandruff<\/li>\n<li>helps against skin impurities<\/li>\n<li>reduces irritations<\/li>\n<li>reduces excess sebum production<\/li>\n<\/ul>\n<\/li>\n<li>manufactured according to good manufacturing practice (GMP)<\/li>\n<li>versatile formulation options (e.g. clear aqueous solutions)<\/li>\n<\/ul>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-tabs accordion toggle_style_1 has_scrolling\" style=\"--sections-title-size:inherit;--sections-gap:0.5rem;\"><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section\" id=\"vafd\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-vafd\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Designations<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-vafd\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column en_b2b_tabelle\"><div class=\"wpb_wrapper\"><table>\n<tbody>\n<tr>\n<td>Trade name<\/td>\n<td><strong>Ichthyol\u00ae Pale<\/strong><\/td>\n<\/tr>\n<tr>\n<td>INCI<\/td>\n<td>Ictasol<\/td>\n<\/tr>\n<tr>\n<td>Synonyms<\/td>\n<td>sodium shale oil sulfonate (former INCI)<br \/>\nIchthyolic Acid, Sodium Salt<\/td>\n<\/tr>\n<tr>\n<td>CAS#<\/td>\n<td>1340-06-3<\/td>\n<\/tr>\n<tr>\n<td>EC#<\/td>\n<td>215-671-7<\/td>\n<\/tr>\n<tr>\n<td>Reach Registration#<\/td>\n<td>01-2120764758-36-0000<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"768\" height=\"1024\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/04\/Berg_01-768x1024.jpeg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/04\/Berg_01-768x1024.jpeg 768w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/04\/Berg_01-225x300.jpeg 225w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/04\/Berg_01.jpeg 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" title=\"\"><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5fb9c346 en_overflow_hide height_large\" id=\"manufacture\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Fish-fossil-from-Seefeld-Paralepidotus-ornatus-1024x768.jpeg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Fish-fossil-from-Seefeld-Paralepidotus-ornatus-1024x768.jpeg 1024w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Fish-fossil-from-Seefeld-Paralepidotus-ornatus-300x225.jpeg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" title=\"\"><\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Manufactured from natural origin&#8221; use_theme_fonts=&#8221;yes&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Ichthyol\u00ae Pale<\/strong> has an exciting history of development. In geoscientific terms, its origin goes back to <strong>deposits of microscopic algae (phytoplankton) in a special lagoon environment of the Alpine region of the Mesozoic era<\/strong>. Under certain conditions, the biodegradation of marine phytoplankton by sulfate-reducing bacteria (anaerobic) allowed the formation of <strong>abundant organically bound sulfur in the biomass<\/strong>. In course of time, diagenetic processes formed <strong>shale-like sedimentary rocks<\/strong> from the periodic deposits, which today contain the marine biomass in solidified form.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-tabs accordion toggle_style_1 has_scrolling\" style=\"--sections-title-size:inherit;--sections-gap:0.5rem;\"><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section\" id=\"d9d9\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-d9d9\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Read more<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-d9d9\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>At the end of geological processes qualitatively appropriate, highly sulfuric deposits of organic matter rich rock are hidden hardly accessible inside the mountains and have to be exploited in a complicated system of underground chambers.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"769\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Mine-Chamber-1024x769.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Mine-Chamber-1024x769.jpg 1024w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Mine-Chamber-300x225.jpg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" title=\"\"><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>In the <strong>dry distillation process<\/strong> that follows mining, the rock is gently heated in the absence of air so that the biomass it contains decomposes only to the point where it can change from a solid to a <strong>liquid form (shale oil pharma)<\/strong>.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_c70c97eb en_overflow_hide height_large\" id=\"manufacture\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Manufacturing in Austria&#8221; use_theme_fonts=&#8221;yes&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Ichthyol\u00ae Pale<\/strong> is manufactured in a dedicated facility in Reith bei Seefeld, Austria. The plant operates in compliance with the requirements for active pharmaceutical ingredients in line with the guidelines of good manufacturing practice (GMP). The GMP system ensures that all I<strong>chthyol\u00ae substances<\/strong> are manufactured reproducibly at the site according to the required (pharmacopoeia) quality.<\/p>\n<p>The shale oil is separated into several fractions in a <strong>vacuum distillation unit<\/strong>. The most volatile of these fractions is used for the production of <strong>Ichthyol\u00ae Pale<\/strong>.<\/p>\n<p>By means of <strong>sulfonation<\/strong> and subsequent <strong>neutralization<\/strong>, the oil is made <strong>water-solubl<\/strong>e. As a result, <strong>Ichthyol\u00ae Pale<\/strong> is obtained as the sodium salt of a pale sulfonated shale oil.<\/p>\n<p>The pale type of <strong>Ichthyol\u00ae (INCI: Ictasol)<\/strong> developed for the cosmetics field is characterized not only by its many beneficial properties, but also by its <strong>high purity, good tolerability and extremely pleasant applicability<\/strong>.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/04\/thomas-henke-mWk5pbVELDU-unsplash-1024x576.jpeg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/04\/thomas-henke-mWk5pbVELDU-unsplash-1024x576.jpeg 1024w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/04\/thomas-henke-mWk5pbVELDU-unsplash-300x169.jpeg 300w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/04\/thomas-henke-mWk5pbVELDU-unsplash.jpeg 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" title=\"\"><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Important to know:<\/strong><\/p>\n<p>The production of <strong>Ichthyol\u00ae substances is not related to the exploitation of crude oil<\/strong> and does not have any petrochemical background. All activities concerning the production of <strong>Ichthyol\u00ae<\/strong> are directed towards pharmaceutical use from the very beginning.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-tabs accordion toggle_style_1 has_scrolling\" style=\"--sections-title-size:inherit;--sections-gap:0.5rem;\"><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section\" id=\"t453\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-t453\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Read more<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-t453\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The <strong>Ichthyol\u00ae substances<\/strong> are derived from <strong>Jurassic limestone<\/strong>, which is rich in <strong>fossil organic substances<\/strong>. The late Kimmeridgian marine limestones of the Orbagnoux area (Rhone, France) are well known for their fish fauna. Commonly, this rock is called oil shale, although it does not meet the definition of shale rock at all. These rocks also do not contain oil. The so-called &#8220;shale oil&#8221; used for the production of the Ichthyol\u00ae substances is first extracted from the <strong>limestone by dry distillation<\/strong>. This shale oil is therefore fundamentally different from crude oil, which is already present in the earth in liquid form and is brought to the surface by pumping (in some cases after fracking) and subsequently used for energy generation or petrochemical purposes. A use of the highly sulfuric shale oil from the limestone deposits in the French Jura that is equivalent to crude oil is completely unthinkable. The focus is solely on pharmaceutical use, to which all production steps are adapted.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5fb9c346 en_overflow_hide height_large\" id=\"application\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Application&#8221; use_theme_fonts=&#8221;yes&#8221;]<\/div><\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Due to <strong>multifunctionality<\/strong> combined with natural origin and good tolerance, <strong>Ichthyol\u00ae Pale<\/strong> is particularly suitable for cosmetic treatment of <strong>dandruff and skin impurities<\/strong>.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-vwrapper align_none valign_top\" style=\"--vwrapper-gap:0.3rem\"><div class=\"w-btn-wrapper align_none\"><a class=\"w-btn us-btn-style_1\" href=\"#dandruff\"><span class=\"w-btn-label\">Dandruff<\/span><\/a><\/div><div class=\"w-btn-wrapper align_none\"><a class=\"w-btn us-btn-style_1\" href=\"#skin-impurities\"><span class=\"w-btn-label\">Skin impurities<\/span><\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_a9be633b en_overflow_hide height_large\" id=\"dandruff\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Dandruff&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;]<\/div><\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Flaking skin problems in the area of the scalp are often triggered or negatively influenced by the interaction of inflammatory processes, excessive microbial colonization or even excessive secretion of sebum. An optimal solution to the irritating problem is ensured by using a <strong>combination of different active principles<\/strong>. <strong>Anti-dandruff shampoos<\/strong> therefore often contain a combination of different active ingredients that address the multifactorial nature of the problem. <strong>Ichthyol\u00ae Pale<\/strong> makes a significant contribution in this regard, as various active principles have been proven for this substance. Among other things, <strong>anti-inflammatory, anti-microbial and antiseborrheic<\/strong> properties have been described. <strong>Ichthyol\u00ae Pale<\/strong> therefore offers the basis for a functionally combined therapy with a single active ingredient (integrated approach).<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Ichthyol\u00ae Pale in the treatment of dandruff &#8211; The benefits at a glance<\/strong><\/p>\n<ul>\n<li>Multifactorial:\n<ul>\n<li>anti-inflammatory<\/li>\n<li>anti-microbial<\/li>\n<li>anti-seborrheic<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><strong>Ichthyol\u00ae Pale &#8211; Benefits in combination shampoos:<\/strong><\/p>\n<ul>\n<li>Provision of valuable additional active properties<\/li>\n<li>Exceptional anti-dandruff effect<\/li>\n<li>Faster and broader effects<\/li>\n<li>Accompanying symptoms are successfully combated<\/li>\n<li>Better tolerance<\/li>\n<li>Reduction of the original concentration of the anti-dandruff active ingredient<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-tabs accordion toggle_style_1 has_scrolling\" style=\"--sections-title-size:inherit;--sections-gap:0.5rem;\"><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section\" id=\"a6f0\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-a6f0\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Studies with Ichthyol\u00ae Pale<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-a6f0\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The efficacy of <strong>Ichthyol\u00ae Pale<\/strong> in the treatment of <strong>dandruff<\/strong> has been impressively confirmed in a number of studies. It has been demonstrated that <strong>Ichthyol\u00ae Pale<\/strong> can be an <strong>alternative<\/strong> to widely obsolete anti-dandruff agents such as <strong>zinc pyrithione or coal tar<\/strong>. Due to the broad spectrum of action of <strong>Ichthyol\u00ae Pale<\/strong>, accompanying symptoms of dandruff such as <strong>reddening of the skin, itching or greasy hair<\/strong> can be effectively treated as well. Often, this is not possible with conventional antidandruff agents, which usually only have an antifungal effect. <strong>Ichthyol\u00ae Pale<\/strong> is superior to Piroctone Olamine in this respect.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"k478\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-k478\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Comparative study with zinc pyrithione and piroctone olamine<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-k478\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>In controlled studies, the efficacy of <strong>1% Ichthyol\u00ae Pale<\/strong> was tested in comparison with commercially available shampoos containing zinc pyrithione and piroctone olamine.<br \/>\nIn all treatment groups, a <strong>significant decrease in dandruff<\/strong> was observed at the end of the study. However, <strong>Ichthyol\u00ae Pale<\/strong> proved to be significantly better than the comparative substances in <strong>eliminating the accompanying symptoms<\/strong> such as itching and thus had an overall advantage.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-image align_none\"><a ref=\"magnificPopup\" href=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Improvement-of-symptoms-scaled.jpg\" aria-label=\"Improvement of symptoms\" class=\"w-image-h\"><img decoding=\"async\" width=\"872\" height=\"1024\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Improvement-of-symptoms-872x1024.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Improvement-of-symptoms-872x1024.jpg 872w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Improvement-of-symptoms-256x300.jpg 256w\" sizes=\"auto, (max-width: 872px) 100vw, 872px\" title=\"\"><\/a><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"r45f\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-r45f\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Comparative study with coal tar<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-r45f\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>An ideal anti-dandruff agent should be a <strong>safe and well-tolerated substance<\/strong> with a broad spectrum of action that eliminates dandruff while at the same time relieving accompanying secondary symptoms (e.g. skin redness). These desirable properties are combined in <strong>Ichthyol\u00ae Pale<\/strong>.<br \/>\nUnquestionably efficient, <strong>coal tar has carcinogenic properties<\/strong>. Even after brief hair washing, critical components of coal tar can be absorbed through the skin. For this reason, <strong>uncontrolled use of coal tar in cosmetics has been banned in Europe<\/strong> since the end of the 1990s.<br \/>\nA comparative study shows that coal tar can be substituted successfully by <strong>Ichthyol\u00ae Pale<\/strong> which proves superior in long-term use due to its good tolerability.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-image align_none\"><a ref=\"magnificPopup\" href=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Average-dandruff-score.jpg\" aria-label=\"Average dandruff score\" class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"746\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Average-dandruff-score-1024x746.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Average-dandruff-score-1024x746.jpg 1024w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Average-dandruff-score-300x219.jpg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" title=\"\"><\/a><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"k684\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-k684\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Combination shampoos<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-k684\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Many known <strong>anti-dandruff agents<\/strong> are potent antifungal agents (e.g. ketoconazole, climbazole, etc.) which, in the context of <strong>dandruff treatment<\/strong>, mainly target the <strong>excessive bacterial colonization of the scalp<\/strong>. However, for a treatment of the overall symptoms, an integrated approach should be chosen that takes into account the entire problem including inflammation, itching and skin redness.<br \/>\nA study was therefore conducted to investigate whether <strong>ketoconazole<\/strong> in combination with <strong>Ichthyol\u00ae Pale<\/strong> offers a broader treatment approach and thus a better prospect of treatment success.<br \/>\nIt was concluded that the combination of <strong>0.5% Ichthyol\u00ae Pale and 0.5% ketoconazole<\/strong> provided <strong>significantly faster elimination of dandruff<\/strong> than treatment with 1.0% ketoconazole alone. In addition, the accompanying symptoms of itching and skin redness were found to subside much more effectively when the active ingredients were combined. This means that when <strong>Ichthyol\u00ae Pale<\/strong> is used, the original concentration of the azole derivative, which is considered to be aggressive, can be halved with an <strong>increase in tolerability without loss of efficacy<\/strong>.<\/p>\n<p>In general, <strong>Ichthyol\u00ae Pale<\/strong> can <strong>boost efficacy<\/strong> in combination shampoos, as synergistic effects also occur with established substances such as salicylic acid.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Please feel free to request more comprehensive information on the active profile of <strong>Ichthyol\u00ae Pale<\/strong>. We will be happy to provide you with literature and support you in developing your own products with <strong>Ichthyol\u00ae Pale<\/strong>.<\/p>\n<\/div><\/div><div class=\"w-separator size_custom\" style=\"height:0.5rem\"><\/div><div class=\"w-btn-wrapper align_none\"><a class=\"w-btn us-btn-style_1\" href=\"\/en\/raw-materials-for-corporate-customers\/contact\/\"><span class=\"w-btn-label\">Contact<\/span><\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_c70c97eb en_overflow_hide height_large\" id=\"skin-impurities\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Skin impurities&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;]<\/div><\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Skin impurities<\/strong> can occur during puberty but also independent of age (e.g. stress-related). Often an <strong>increased secretion of sebum<\/strong> in the sebaceous glands plays an important role. If a plug is formed in the excretory duct of the sebaceous glands, <strong>the accumulated sebum is an ideal nutrient medium for certain bacteria<\/strong>. Certain enzymes (lipases) enable the bacteria to decompose the sebum to form free fatty acids. The free fatty acids in turn penetrate into the surrounding tissue, where they provoke inflammatory phenomena such as redness and pimples.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Ichthyol\u00ae Pale for skin impurities &#8211; The advantages at a glance<\/strong><\/p>\n<ul>\n<li>Multifunctional\n<ul>\n<li>anti-microbial<\/li>\n<li>anti-inflammatory<\/li>\n<li>anti-seborrheic<\/li>\n<\/ul>\n<\/li>\n<li>Well tolerated<\/li>\n<li>Natural origin<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-tabs accordion toggle_style_1 has_scrolling\" style=\"--sections-title-size:inherit;--sections-gap:0.5rem;\"><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section\" id=\"ke02\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-ke02\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">How Ichthyol\u00ae Pale helps<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-ke02\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Skin blemishes are often triggered or negatively influenced by the interaction of inflammatory processes, excessive microbial colonization and excessive secretion of sebum. In the care of irritated skin, <strong>Ichthyol\u00ae Pale<\/strong> can make a significant contribution, as various active principles have been proven for this substance that address the overall problem outlined above. <strong>Anti-inflammatory, antimicrobial and antiseborrheic properties<\/strong> are described for <strong>Ichthyol\u00ae Pale<\/strong>. <strong>Ichthyol\u00ae Pale<\/strong> therefore provides the basis for a functionally combined care regimen with a single active substance.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"p0aa\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-p0aa\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">The anti-irritant effect<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-p0aa\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The <strong>anti-inflammatory effect of Ichthyol\u00ae Pale<\/strong> was clearly demonstrated in the UVB erythema test. The skin redness of test subjects was reduced when treated with <strong>4\u00a0% Ichthyol\u00ae Pale<\/strong> in a cream comparable to a 0.5\u00a0% hydrocortisone ointment.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-image align_none\"><a ref=\"magnificPopup\" href=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/comparison-of-skin-color.jpg\" aria-label=\"comparison of skin color\" class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"746\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/comparison-of-skin-color-1024x746.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/comparison-of-skin-color-1024x746.jpg 1024w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/comparison-of-skin-color-300x219.jpg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" title=\"\"><\/a><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>At the cellular level, it was observed that <strong>Ichthyol\u00ae Pale inhibits the activity of enzymes<\/strong> that catalyze the formation of inflammation mediators. Inflammatory mediators are involved in the development of inflammation (e.g. redness). In the presence of <strong>Ichthyol\u00ae Pale<\/strong>, the enzyme 5-lipoxygenase, for example, is inhibited in a concentration-dependent manner, which significantly impairs the formation of the inflammatory mediator LTB4.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"s240\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-s240\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">The anti-microbial effect<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-s240\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Ichthyol\u00ae Pale<\/strong> exhibits antimicrobial effects with all germs that are relevant in cosmetically significant skin problems.<br \/>\nIn the case of skin blemishes, Propionibacterium acnes is particularly noteworthy, for which <strong>Ichthyol\u00ae Pale<\/strong> is highly active with a minimum inhibitory concentration (MIC) of 0.039%.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"rdc7\"><button type=\"button\" class=\"w-tabs-section-header\" aria-controls=\"content-rdc7\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Studies<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-rdc7\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The combination of the anti-inflammatory and antimicrobial properties of <strong>Ichthyol\u00ae Pale<\/strong> leads to very good results in the <strong>elimination of skin impurities (pimples)<\/strong>. This was the conclusion of a study conducted on <strong>101 test subjects using a 1% Ichthyol\u00ae Pale formulation<\/strong>. After a treatment phase of six weeks, efficacy was rated as <strong>&#8220;good&#8221; or &#8220;very good&#8221; in around 76\u00a0%<\/strong> of cases.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-image align_none\"><a ref=\"magnificPopup\" href=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Effect-percent-on-subjects.jpg\" aria-label=\"Effect percent on subjects\" class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"806\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Effect-percent-on-subjects-1024x806.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Effect-percent-on-subjects-1024x806.jpg 1024w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Effect-percent-on-subjects-300x236.jpg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" title=\"\"><\/a><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>In another study, the effectiveness of a formulation containing <strong>1\u00a0% Ichthyol\u00ae Pale and 0.5\u00a0% salicylic acid<\/strong> was tested. In the course of the eight-week treatment phase, the average number of visible skin lesions was reduced from 31.4 to 6.3, corresponding to a <strong>decrease of approximately 80\u00a0%<\/strong>.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-image align_none\"><a ref=\"magnificPopup\" href=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Number-of-efflorescences.jpg\" aria-label=\"Number of efflorescences\" class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"806\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Number-of-efflorescences-1024x806.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Number-of-efflorescences-1024x806.jpg 1024w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Number-of-efflorescences-300x236.jpg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" title=\"\"><\/a><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>In addition to the efficacy of <strong>Ichthyol\u00ae Pale<\/strong>, its tolerability was also rated as &#8220;good&#8221; to &#8220;very good&#8221; in both studies.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Please contact us for further information on the action profile of <strong>Ichthyol\u00ae Pale<\/strong>. We will be happy to support you in your development projects and provide you with framework formulations.<\/p>\n<\/div><\/div><div class=\"w-separator size_custom\" style=\"height:0.5rem\"><\/div><div class=\"w-btn-wrapper align_none\"><a class=\"w-btn us-btn-style_1\" href=\"\/en\/raw-materials-for-corporate-customers\/contact\/\"><span class=\"w-btn-label\">Contact<\/span><\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5fb9c346 en_overflow_hide height_large\" id=\"product-development\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Product development&#8221; use_theme_fonts=&#8221;yes&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Product development with Ichthyol\u00ae Pale<\/strong> &#8211; What should be considered?<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Ichthyol\u00ae Pale<\/strong> can generally be <strong>formulated in a wide range of concentrations (recommended 0.5 &#8211; 5%)<\/strong>. Some raw material properties must be taken into account in order to achieve the intended results in formulations.<\/p>\n<ul>\n<li><strong>Ichthyol\u00ae Pale<\/strong> is a <strong>sulfonate salt<\/strong> of a highly volatile, extremely sulfur-rich shale oil fraction in aqueous solution. <strong>It is not an oil.<\/strong> The symbolized formula can be represented by R-SO3Na (R = organic fraction of phytoplanktonic origin).<\/li>\n<li>As a sulfonate salt, <strong>Ichthyol\u00ae Pale<\/strong> has <strong>surfactant properties<\/strong> (lipophilic (R) and hydrophilic component (SO3Na) in the molecule) and is therefore <strong>surface active<\/strong>.<\/li>\n<li>In principle, <strong>hydrophilic creams<\/strong> are formed <strong>in preference<\/strong> to those of lipophilic character.<\/li>\n<li><strong>Miscibility<\/strong> with oils without emulsifier is generally not possible. However, the s<strong>olubility of Ichthyol\u00ae Pale in water, glycerin or alcohol-water mixtures<\/strong> is normally <strong>without problems.<\/strong><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><ul>\n<li>In solutions, precipitation may occur when additional salts are added. Cations of higher valency and salting out must be avoided.<\/li>\n<li><strong>Ichthyol\u00ae Pale<\/strong> is stable over a wide <strong>pH<\/strong> range. Only strong acids cause precipitation.<\/li>\n<li><strong>Ichthyol\u00ae Pale<\/strong> has <strong>antimicrobial properties<\/strong>. The use of <strong>preservatives can be limited<\/strong> if appropriate.<\/li>\n<li>In closed, well-filled containers, <strong>Ichthyol\u00ae Pale<\/strong> has a <strong>shelf life of at least 48 months<\/strong>, provided the storage conditions are observed.<\/li>\n<\/ul>\n<p>For further information on formulating with <strong>Ichthyol\u00ae Pale<\/strong>, please feel free to <a href=\"https:\/\/www.ichthyol.de\/en\/raw-materials-for-corporate-customers\/contact\/\">contact us<\/a>. We will be happy to provide you with <strong>detailed frame formulations<\/strong> for shampoos, creams, pastes, etc. on request.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_a9be633b en_overflow_hide height_large\" id=\"safety-assessment\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default reversed stacking_default\"><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Safety assessment&#8221; use_theme_fonts=&#8221;yes&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The good tolerability of <strong>Ichthyol\u00ae Pale<\/strong> has been demonstrated in a large number of toxicological studies. <strong>Ichthyol\u00ae Pale<\/strong> proved to be <strong>well tolerated<\/strong> both with short-term and long-term administration. There were no indications of teratogenic, mutagenic or carcinogenic properties.<\/p>\n<p>The safety of a cosmetic raw material such as <strong>Ichthyol\u00ae Pale<\/strong> is best illustrated by <strong>calculating the safety factor<\/strong>. For both rinse-off and leave-on products, the <strong>safety factors<\/strong> obtained with <strong>Ichthyol\u00ae Pale<\/strong> in the usual use concentrations are clearly <strong>above the required minimum value of 100<\/strong>.<\/p>\n<p>We offer our customers <strong>comprehensive documentation<\/strong> for the <strong>safety assessment<\/strong> of their cosmetics. Let us know if you need any information.<\/p>\n<\/div><\/div><div class=\"w-separator size_custom\" style=\"height:0.5rem\"><\/div><div class=\"w-btn-wrapper align_none\"><a class=\"w-btn us-btn-style_1\" href=\"\/en\/raw-materials-for-corporate-customers\/contact\/\"><span class=\"w-btn-label\">Contact<\/span><\/a><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"642\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Frau-mit-Mikroskop-im-Labor-1024x642.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Frau-mit-Mikroskop-im-Labor-1024x642.jpg 1024w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Frau-mit-Mikroskop-im-Labor-300x188.jpg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" title=\"\"><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_c70c97eb en_overflow_hide height_large\" id=\"differentiation\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-2 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><div class=\"vc_col-sm-8 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Differentiation from Tars&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Since 1996, cosmetic coal tar shampoos may no longer be manufactured in the EU due to the toxicity of the tar. <strong>Ichthyol\u00ae Pale is recommended as an alternative to coal tar.<\/strong><\/p>\n<p>Because of their characteristic odor and related spectrum of action, sulfonated shale oils are sometimes assigned to tars. However, <strong>Ichthyol\u00ae Pale<\/strong> and tars differ very substantially with regard to:<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-2 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><div class=\"w-separator size_medium\"><\/div><div class=\"g-cols wpb_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column en_wirkstoff_tabelle\"><div class=\"wpb_wrapper\"><table>\n<tbody>\n<tr>\n<td><\/td>\n<td><strong>Ichthyol\u00ae Pale<\/strong><\/td>\n<td><strong>Coal tar<\/strong><\/td>\n<\/tr>\n<tr>\n<td><strong>Origin<\/strong><\/td>\n<td>Limestone with biomass from marine phytoplankton<\/td>\n<td>Coal from land plants<\/td>\n<\/tr>\n<tr>\n<td><strong>Dry distillation<\/strong><\/td>\n<td>From approx. 300\u00b0C<\/td>\n<td>At approx. 1000\u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Active Substance<\/strong><\/td>\n<td>Sulfonated shale oil<\/td>\n<td>Coal tar<\/td>\n<\/tr>\n<tr>\n<td><strong>Properties<\/strong><\/td>\n<td>\n<ul>\n<li>Salts in aqueous solution<\/li>\n<li>Water-soluble<\/li>\n<li>Rich in sulfur<\/li>\n<li>Low in phenols<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li>Mixture of hydrocarbons and phenols<\/li>\n<li>Not water-soluble<\/li>\n<li>Low in sulfur<\/li>\n<li>Rich in phenols<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td><strong>Contamination with polycyclic aromatic hydrocarbons (benzo[a]pyrene)<\/strong><\/td>\n<td>High purity with respect to PAHs<br \/>\n(&amp;lt 0.001 ppm benzo[a]pyrene)<\/td>\n<td>Highly contaminated with PAHs<br \/>\n(&amp;gt 5000 ppm benzo[a]pyrene)<\/td>\n<\/tr>\n<tr>\n<td><strong>Influence on the genetic material<\/strong><\/td>\n<td>No<\/td>\n<td>Indications of genetic alteration<\/td>\n<\/tr>\n<tr>\n<td><strong>Carcinogenic<\/strong><\/td>\n<td>No<\/td>\n<td>Indication of carcinogenic effects<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_5fb9c346 en_overflow_hide height_large\" id=\"offers\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_middle type_default reversed stacking_default\"><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">[vc_custom_heading text=&#8221;Offers and further information&#8221; use_theme_fonts=&#8221;yes&#8221;]<div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><a href=\"https:\/\/www.ichthyol.de\/en\/raw-materials-for-corporate-customers\/contact\/\">Contact<\/a> us for a quotation on <strong>Ichthyol\u00ae Pale<\/strong> in the quantity you require. We usually deliver <strong>worldwide at short notice<\/strong> directly from our GMP warehouse in Hamburg in <strong>container sizes (HDPE) of 1 kg, 5 kg, 25 kg and 200 kg<\/strong>. Upon prior arrangement, we will be happy to provide you with <strong>samples free of charge<\/strong> for development work.<\/p>\n<p><strong>The use of Ichthyol\u00ae Pale is possible worldwide.<\/strong> For use in China, the registration code is available under the new Chinese cosmetic law since spring 2022.<\/p>\n<p>For <strong>Ichthyol\u00ae Pale<\/strong> we offer an extensive cosmetic oriented documentation.<\/p>\n<p>For regulatory and scientific questions as well as for availability of <strong>Ichthyol\u00ae Pale<\/strong> in a specific distribution area, please feel free to contact us.<\/p>\n<p>You can find our terms and conditions <a href=\"\/wp-content\/uploads\/2022\/09\/General_Terms_and_Conditions_of_Delivery_and_Sales_-_ICHTHYOL_-_raw_materials.pdf\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Your Ichthyol\u00ae Team<\/strong><\/p>\n<p>Phone +49 40 50714 -108 \/ -180 \/ -360 \/ -367<br \/>\neMail <a href=\"mailto:rawmaterial@ichthyol.com\">rawmaterial@ichthyol.com<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-12 vc_col-lg-6 vc_col-md-6 vc_col-xs-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Ichthyol-Pale-drums-1024x768.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Ichthyol-Pale-drums-1024x768.jpg 1024w, https:\/\/www.ichthyol.de\/wp-content\/uploads\/2022\/09\/Ichthyol-Pale-drums-300x225.jpg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" title=\"\"><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"[vc_custom_heading text=\"Ichthyol\u00ae Pale\" font_container=\"tag:h1|text_align:center\" use_theme_fonts=\"yes\"]By the name of Ichthyol\u00ae Pale, Ichthyol-Gesellschaft offers pale sulfonated shale oil for use in cosmetic skin and hair care. Convince yourself of the quality and proven efficacy profile of this well-tolerated substance on the following pages. Flyer[vc_custom_heading text=\"A guarantee for good quality\" use_theme_fonts=\"yes\"]Flaking scalp and skin problems as well as...","protected":false},"author":13,"featured_media":0,"parent":4952,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-4969","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ichthyol.de\/en\/wp-json\/wp\/v2\/pages\/4969","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ichthyol.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ichthyol.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ichthyol.de\/en\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ichthyol.de\/en\/wp-json\/wp\/v2\/comments?post=4969"}],"version-history":[{"count":0,"href":"https:\/\/www.ichthyol.de\/en\/wp-json\/wp\/v2\/pages\/4969\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.ichthyol.de\/en\/wp-json\/wp\/v2\/pages\/4952"}],"wp:attachment":[{"href":"https:\/\/www.ichthyol.de\/en\/wp-json\/wp\/v2\/media?parent=4969"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}